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Phosphatidylserine Ingredient Notes
Phosphatidylserine, or PS, is a phospholipid found in cell membranes. A phospholipid mixture such as lecithin is not the same as its individual PS content.

Phosphatidylserine, or PS, is a phospholipid found in cell membranes. A phospholipid mixture such as lecithin is not the same as its individual PS content.
Community experiences
Selected positive personal experiences from external communities, edited and summarized. These accounts do not establish effectiveness.
A contributor with memory difficulties following encephalitis wrote that their performance on word-list recall tests and at work improved while using phosphatidylserine. They reported more than ten years of use but clearly stated that some memory difficulties remained. They provided neither the original test data nor details of other treatment or rehabilitation, so this is not a verified recovery from the aftereffects of encephalitis or a report of complete recovery.
Experience shared by external community contributor A
A contributor who took phosphatidylserine softgels before bed wrote that they found it easier to fall asleep and stay asleep. They selected a duration of at least one but less than two years of use in their review. Without specific sleep-duration data, details of other treatments or the full product formula, the account should not be read as an improvement confirmed by a sleep study or as an insomnia-treatment outcome.
Experience shared by external community contributor B
This page is for general reference only and is not medical advice, diagnosis, treatment, or prescription. Ask a qualified professional if you need medical advice or diagnosis.
What is Phosphatidylserine?
Phosphatidylserine, or PS, is a phospholipid found in cell membranes. A phospholipid mixture such as lecithin is not the same as its individual PS content.
On Supplecipe, you can search iHerb products that mention Phosphatidylserine and compare single-ingredient products against broader supplement blends.
Evidence and limitations
A 15-week trial randomized 157 older adults with memory complaints but without dementia to an omega-3-containing PS preparation or placebo. Immediate verbal recall improved with PS-DHA. This exploratory result does not establish the same benefits for every PS-only product or focus in younger people.
Forms and other names
Phosphatidylserine and PS identify this phospholipid. Phosphatidylcholine (PC) is a different ingredient; check sources such as soy or sunflower.
Related ingredients
Related reading, not a recommendation to combine supplements.
Side effects and cautions
Check source ingredients and allergen statements if you have a soy or other allergy. Persistent memory decline or changes that affect everyday life need assessment rather than self-treatment with supplements.
How to compare iHerb products
- Distinguish total phospholipid-complex weight from the amount of PS supplied per serving. Check the source and separately declared omega-3 or other phospholipid amounts.
- Look for form, serving size, extra ingredients, allergens, and whether the product is a single ingredient or a blend.
- Compare brand, price per serving, ingredient form, and single-ingredient versus complex products.
- Use the search button below to compare iHerb products that mention this ingredient.
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